Paracrine IL-6 Signaling Confers Proliferation between Heterogeneous Inflammatory Breast Cancer Sub-Clones

Paracrine IL-6 Signaling Confers Proliferation between Heterogeneous Inflammatory Breast Cancer Sub-Clones

Inflammatory breast cancer (IBC) describes a highly aggressive form of breast cancer of diverse molecular subtypes and clonal heterogeneity across individual tumors. Accordingly, IBC is recognized by its clinical signs of inflammation, associated with expression of interleukin (IL)-6 and other infla...

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Bibliographic Details
Main Authors: Allam, A.H (Author), Deb, S. (Author), Ernst, M. (Author), Johnstone, C.N (Author), Lim, E. (Author), Morrow, R.J (Author), Murone, C. (Author), Yeo, B. (Author)
Format: Article
Language:English
Published: MDPI 2022
Subjects:
HER2
heterogeneity
inflammatory breast cancer
interleukin-6
paracrine
pSTAT3
Tocilizumab
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