LDH-A—Modulation and the Variability of LDH Isoenzyme Profiles in Murine Gliomas: A Link with Metabolic and Growth Responses

Three murine glioma cell lines (GL261, CT2A, and ALTS1C1) were modified to downregu-late the expression of the murine LDH-A gene using shRNA, and compared to shRNA scrambled control (NC) cell lines. Differences in the expression of LDH-A and LDH-B mRNA, protein and enzymatic activity, as well as the...

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Bibliographic Details
Main Authors: Albeg, A.S (Author), Blasberg, R. (Author), Cohen, I.J (Author), Maeda, M. (Author), Mane, M.M (Author), Myat, K. (Author), Serganova, I. (Author), Shindo, M. (Author), Vemuri, K. (Author)
Format: Article
Language:English
Published: MDPI 2022
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