Store-Operated Ca2+ Entry Is Up-Regulated in Tumour-Infiltrating Lymphocytes from Metastatic Colorectal Cancer Patients

Store-Operated Ca2+ Entry Is Up-Regulated in Tumour-Infiltrating Lymphocytes from Metastatic Colorectal Cancer Patients

(1) Background: Store-operated Ca2+ entry (SOCE) drives the cytotoxic activity of cytotoxic T lymphocytes (CTLs) against cancer cells. However, SOCE can be enhanced in cancer cells due to an increase in the expression and/or function of its underlying molecular components, i.e., STIM1 and Orai1. Her...

Full description

Bibliographic Details
Main Authors: Conca, F. (Author), Faris, P. (Author), Lefkimmiatis, K. (Author), Lim, D. (Author), Metallo, A. (Author), Moccia, F. (Author), Montagna, D. (Author), Negri, S. (Author), Pedrazzoli, P. (Author), Rumolo, A. (Author), Tanzi, M. (Author), Tapella, L. (Author)
Format: Article
Language:English
Published: MDPI 2022
Subjects:
BTP-2
colorectal carcinoma
diacylglycerol kinase
store-operated Ca2+ entry
tumour-infiltrating lymphocytes
Online Access:View Fulltext in Publisher

Internet

View Fulltext in Publisher

Similar Items