Shifting CCR7 towards Its Monomeric Form Augments CCL19 Binding and Uptake

The chemokine receptor CCR7, together with its ligands, is responsible for the migration and positioning of adaptive immune cells, and hence critical for launching adaptive immune responses. CCR7 is also induced on certain cancer cells and contributes to metastasis formation. Thus, CCR7 expression a...

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Bibliographic Details
Main Authors: Artinger, M. (Author), Gerken, O.J (Author), Legler, D.F (Author)
Format: Article
Language:English
Published: MDPI 2022
Subjects:
Online Access:View Fulltext in Publisher