IL-3-Induced Immediate Expression of c-fos and c-jun Is Modulated by the IKK2-JNK Axis

Interleukin (IL)-3 is a pleiotropic cytokine that regulates the survival, proliferation, and differentiation of hematopoietic cells. The binding of IL-3 to its receptor activates intracellular signaling, inducing transcription of immediate early genes (IEGs) such as c-fos, c-jun, and c-myc; however,...

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Bibliographic Details
Main Authors: Fujii, H. (Author), Fujita, H. (Author), Fujita, T. (Author)
Format: Article
Language:English
Published: MDPI 2022
Subjects:
IKK
JNK
Online Access:View Fulltext in Publisher