Identification of Putative Plant-Based ALR-2 Inhibitors to Treat Diabetic Peripheral Neuropathy

Identification of Putative Plant-Based ALR-2 Inhibitors to Treat Diabetic Peripheral Neuropathy

Diabetic peripheral neuropathy (DPN) is a common diabetes complication (DM). Aldose reductase-2 (ALR-2) is an oxidoreductase enzyme that is most extensively studied therapeutic target for diabetes-related complications that can be inhibited by epalrestat, which has severe adverse effects; hence the...

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Bibliographic Details
Main Authors: Abdelgadir, A. (Author), Alabdallah, N.M (Author), Alam, M.J (Author), Al-Shammary, A. (Author), Badroui, R. (Author), El Asmar, Z. (Author), Kausar, M.A (Author), Saeed, M. (Author), Shoib, A. (Author), Sulieman, A.M.E (Author), Tasleem, M. (Author), Zahin, M. (Author)
Format: Article
Language:English
Published: MDPI 2022
Subjects:
ADMET
molecular docking
NuBBEDB
pharmacophore
structure-based drug design
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