Amorphigenin from Amorpha fruticosa L. Root Extract Induces Autophagy-Mediated Melanosome Degradation in mTOR-Independent-and AMPK-Dependent Manner

Amorphigenin from Amorpha fruticosa L. Root Extract Induces Autophagy-Mediated Melanosome Degradation in mTOR-Independent-and AMPK-Dependent Manner

In this study, we investigated the depigmentation effect of Amorpha fruticosa L. root extract (RE), an herbal medicine. A. fruticosa RE significantly induced depigmentation in α-MSH-treated B16F10 cells at noncytotoxic concentrations. Further, the RE decreased the protein levels of the melanosomal p...

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Bibliographic Details
Main Authors: Hwangbo, C. (Author), Kim, J. (Author), Kim, J.Y (Author), Kim, K.D (Author), Kim, M. (Author), Lee, K.W (Author), Lee, S.H (Author), Lim, S. (Author), Nguyen, D.T (Author), Park, K.H (Author), Yoo, J. (Author)
Format: Article
Language:English
Published: MDPI 2022
Subjects:
Amorpha fruticosa L
amorphigenin
AMPK
autophagy
depigmentation
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