Rosmarinic Acid, as an NHE1 Activator, Decreases Skin Surface pH and Improves the Skin Barrier Function

Rosmarinic Acid, as an NHE1 Activator, Decreases Skin Surface pH and Improves the Skin Barrier Function

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Stratum corneum (SC) pH regulates skin barrier functions and elevated SC pH is an important factor in various inflammatory skin diseases. Acidic topical formulas have emerged as treatments for impaired skin barriers. Sodium proton exchanger 1 (NHE1) is an important factor in SC acidification. We inv...

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Bibliographic Details
Main Authors: Chang, M.Y (Author), Choi, E.H (Author), Jung, S.-W (Author), Kim, E. (Author), Kim, H.W (Author), Lee, J.S (Author), Park, G.H (Author), Park, K. (Author), Shin, K.-O (Author), Yoo, K.M (Author)
Format: Article
Language:English
Published: NLM (Medline) 2022
Subjects:
adult
Adult
Cinnamates
cinnamic acid
depside
Depsides
epidermis
Epidermis
female
Female
human
Humans
Hydrogen-Ion Concentration
Melissa officinalis leaf extract
metabolism
middle aged
Middle Aged
pH
rosmarinic acid
skin
Skin
skin barrier
skin pH
sodium proton exchanger 1
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