Metalloendopeptidase ADAM-like Decysin 1 (ADAMDEC1) in Colonic Subepithelial PDGFRα+ Cells Is a New Marker for Inflammatory Bowel Disease

Metalloendopeptidase ADAM-like Decysin 1 (ADAMDEC1) in Colonic Subepithelial PDGFRα+ Cells Is a New Marker for Inflammatory Bowel Disease

Metalloendopeptidase ADAM-Like Decysin 1 (ADAMDEC1) is an anti-inflammatory peptidase that is almost exclusively expressed in the gastrointestinal (GI) tract. We have recently found abundant and selective expression of Adamdec1 in colonic mucosal PDGFRα+ cells. However, the cellular origin for this...

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Main Authors: Baek, G. (Author), Bartlett, A. (Author), Becker, L. (Author), Choi, S.-C (Author), Gottfried-Blackmore, A. (Author), Ha, S.E (Author), Habtezion, A. (Author), Jin, B. (Author), Jorgensen, B.G (Author), Kim, M.-S (Author), Kim, S. (Author), Kim, Y.-S (Author), Kurahashi, M. (Author), Lee, M.-Y (Author), Poudrier, S.M (Author), Ro, S. (Author), Rubin, S.J.S (Author), Sanders, K.M (Author), Sasse, K.C (Author), Singh, R. (Author), Wei, L. (Author), Zogg, H. (Author)
Format: Article
Language:English
Published: MDPI 2022
Subjects:
ADAMDEC1
Crohn’s disease
DSS colitis
inflammatory bowel disease
mucosal PDGFRα+ cells
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