Association of Ligamentum Flavum Hypertrophy with Adolescent Idiopathic Scoliosis Progression—Comparative Microarray Gene Expression Analysis

Association of Ligamentum Flavum Hypertrophy with Adolescent Idiopathic Scoliosis Progression—Comparative Microarray Gene Expression Analysis

The role of the ligamentum flavum (LF) in the pathogenesis of adolescent idiopathic scoliosis (AIS) is not well understood. Using magnetic resonance imaging (MRI), we investigated the degrees of LF hypertrophy in 18 patients without scoliosis and on the convex and concave sides of the apex of the cu...

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Bibliographic Details
Main Authors: Futakawa, H. (Author), Hirokawa, T. (Author), Iwasaki, M. (Author), Kamei, K. (Author), Kawaguchi, Y. (Author), Kondo, M. (Author), Makino, H. (Author), Nogami, M. (Author), Seki, S. (Author), Tran Canh Tung, N. (Author), Tsuji, M. (Author), Watanabe, K. (Author), Yahara, Y. (Author)
Format: Article
Language:English
Published: MDPI 2022
Subjects:
adolescent idiopathic scoliosis
elastic fiber
interleukin-6
ligamentum flavum
microarray analysis
TGF-β signaling
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