Urocortin-1 Is Chondroprotective in Response to Acute Cartilage Injury via Modulation of Piezo1

Post-traumatic OA (PTOA) is often triggered by injurious, high-impact loading events which result in rapid, excessive chondrocyte cell death and a phenotypic shift in residual cells toward a more catabolic state. As such, the identification of a disease-modifying OA drug (DMOAD) that can protect cho...

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Bibliographic Details
Main Authors: Higgins, S.M (Author), Jones, R.C (Author), Lawrence, K.M (Author), Richardson, S.M (Author), Townsend, P.A (Author)
Format: Article
Language:English
Published: MDPI 2022
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Online Access:View Fulltext in Publisher