Solvent Vibrations as a Proxy of the Telomere G-Quadruplex Rearrangements across Thermal Unfolding

G-quadruplexes (G4s) are noncanonical forms of DNA involved in many key genome functions. Here, we exploited UV Resonance Raman scattering to simultaneously explore the vibrational behavior of a human telomeric G4 (Tel22) and its aqueous solvent as the biomolecule underwent thermal melting. We found...

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Bibliographic Details
Main Authors: Bianchi, F. (Author), Comez, L. (Author), D’amico, F. (Author), Libera, V. (Author), Masciovecchio, C. (Author), Paciaroni, A. (Author), Petrillo, C. (Author), Rossi, B. (Author), Sacchetti, F. (Author)
Format: Article
Language:English
Published: MDPI 2022
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