Polyamine Oxidase Expression Is Downregulated by 17β-Estradiol via Estrogen Receptor 2 in Human MCF-7 Breast Cancer Cells

Polyamine levels decrease with menopause; however, little is known about the mechanisms regulated by menopause. In this study, we found that among the genes involved in the polyamine pathway, polyamine oxidase (PAOX) mRNA levels were the most significantly reduced by treatment with 17β-estradiol in...

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Bibliographic Details
Main Authors: Kim, J.H (Author), Lee, S.-T (Author)
Format: Article
Language:English
Published: MDPI 2022
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Online Access:View Fulltext in Publisher