Immunophenotypic Alterations in Adult Patients with Steroid-Dependent and Frequently Relapsing Nephrotic Syndrome

Immunophenotypic Alterations in Adult Patients with Steroid-Dependent and Frequently Relapsing Nephrotic Syndrome

Immune dysregulation plays a key role in the pathogenesis of steroid-dependent/frequently relapsing nephrotic syndrome (SDNS/FRNS). However, in contrast with evidence from the pediatric series, no major B- or T-cell alterations have been described for adults. In these patients, treatment with rituxi...

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Bibliographic Details
Main Authors: Benigni, A. (Author), Carrara, C. (Author), Casiraghi, F. (Author), Diadei, O. (Author), Mister, M. (Author), Podestà, M.A (Author), Remuzzi, G. (Author), Ruggiero, B. (Author), Todeschini, M. (Author), Trillini, M. (Author), Villa, A. (Author)
Format: Article
Language:English
Published: MDPI 2023
Subjects:
B cells
nephrotic syndrome
regulatory T cells
rituximab
steroid-dependent nephrotic syndrome
steroid-resistant nephrotic syndrome
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