Phosphorylation of Neurofilament Light Chain in the VLO Is Correlated with Morphine-Induced Behavioral Sensitization in Rats

Phosphorylation of Neurofilament Light Chain in the VLO Is Correlated with Morphine-Induced Behavioral Sensitization in Rats

Neurofilament light chain (NF-L) plays critical roles in synapses that are relevant to neuropsychiatric diseases. Despite postmortem evidence that NF-L is decreased in opiate abusers, its role and underlying mechanisms remain largely unknown. We found that the microinjection of the histone deacetyla...

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Bibliographic Details
Main Authors: Chen, J. (Author), Chen, Z.-N (Author), Gao, F.-F (Author), Gao, J.-Q (Author), Huo, F.-Q (Author), Yan, C.-X (Author), Yang, J.-S (Author), Yang, X.-X (Author), Yu, D.-Y (Author), Zhang, Y.-X (Author), Zhu, Y.-M (Author)
Format: Article
Language:English
Published: MDPI 2023
Subjects:
animal
Animals
cAMP response element-binding protein (CREB)
extracellular signal-regulated kinase (ERK)
histone deacetylase inhibitor
Histone Deacetylase Inhibitors
histone deacetylases
intermediate filament
Intermediate Filaments
learning
Learning
morphine
Morphine
neurofilament light subunit (NF-L)
phosphorylation
Phosphorylation
rat
Rats
Rats, Sprague-Dawley
Sprague Dawley rat
ventrolateral orbital cortex
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