Transcriptomics and Phenotypic Analysis of gpr56 Knockout in Zebrafish

Transcriptomics and Phenotypic Analysis of gpr56 Knockout in Zebrafish

The adhesion G-protein-coupled receptor is a seven-transmembrane receptor protein with a complex structure. Impaired GPR56 has been found to cause developmental damage to the human brain, resulting in intellectual disability and motor dysfunction. To date, studies on gpr56 deficiency in zebrafish ha...

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Bibliographic Details
Main Authors: Ao, J. (Author), Peng, Z. (Author), Qin, B. (Author), Sun, L. (Author), Wang, J. (Author), Xie, H. (Author), Yang, B. (Author), Yang, T. (Author), Yang, Y. (Author), Zheng, L. (Author)
Format: Article
Language:English
Published: MDPI 2023
Subjects:
adolescent
animal experiment
article
cold stress
controlled study
CRISPR-CAS9 system
differential gene expression
differentially expressed genes
exocrine gland
female
fertilization
gene deletion
gene editing
gene expression
gene mutation
genetic transcription
gpr56
homozygote
in situ hybridization
innate immunity
juvenile
knockout
knockout gene
male
motor ability
motor function test
nonhuman
pancreas
protein expression
protein function
quantitative analysis
real time polymerase chain reaction
RNA sequencing
RNA-seq
transcriptomics
zebra fish
zebrafish
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