AI-Predicted mTOR Inhibitor Reduces Cancer Cell Proliferation and Extends the Lifespan of C. elegans

The mechanistic target of rapamycin (mTOR) kinase is one of the top drug targets for promoting health and lifespan extension. Besides rapamycin, only a few other mTOR inhibitors have been developed and shown to be capable of slowing aging. We used machine learning to predict novel small molecules ta...

Full description

Bibliographic Details
Main Authors: Dakhovnik, A. (Author), Ewald, C.Y (Author), Hrabovskyi, O. (Author), MacArthur, M.R (Author), Vidovic, T. (Author)
Format: Article
Language:English
Published: MDPI 2023
Subjects:
Online Access:View Fulltext in Publisher
View in Scopus