Uremic Toxin Indoxyl Sulfate Promotes Macrophage-Associated Low-Grade Inflammation and Epithelial Cell Senescence

Uremic Toxin Indoxyl Sulfate Promotes Macrophage-Associated Low-Grade Inflammation and Epithelial Cell Senescence

In this study, we investigated the impact of the uremic toxin indoxyl sulfate on macrophages and tubular epithelial cells and its role in modulating the response to lipopolysaccharide (LPS). Indoxyl sulfate accumulates in the blood of patients with chronic kidney disease (CKD) and is a predictor of...

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Bibliographic Details
Main Authors: Adamowicz, K. (Author), Anders, H.-J (Author), Koziel, J. (Author), Lech, M. (Author), Liu, F. (Author), Ribeiro, A. (Author), Rother, S. (Author), Schmaderer, C. (Author), Srebrzynski, M. (Author), Steiger, S. (Author), Wadowska, M. (Author)
Format: Article
Language:English
Published: MDPI 2023
Subjects:
CKD
indoxyl sulfate
inflammaging
inflammation
macrophage
senescence
uremic toxins
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