Differential Effects of Overexpression of Wild Type and Kinase-Dead MELK in Fibroblasts and Keratinocytes, Potential Implications for Skin Wound Healing and Cancer

Maternal embryonic leucine-zipper kinase (MELK) plays a significant role in cell cycle progression, mitosis, cell migration, cell renewal, gene expression, embryogenesis, proliferation, apoptosis, and spliceosome assembly. In addition, MELK is known to be overexpressed in multiple types of cancer an...

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Bibliographic Details
Main Authors: Kubiak, J.Z (Author), Lewicki, S. (Author), Lieto, K. (Author), Szymański, Ł. (Author), Tassan, J.-P (Author), Zdanowski, R. (Author)
Format: Article
Language:English
Published: MDPI 2023
Subjects:
ERK
JNK
p38
p53
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