Combined Transcriptome and Metabolome Analysis of Smooth Muscle of Myostatin Knockout Cattle

Combined Transcriptome and Metabolome Analysis of Smooth Muscle of Myostatin Knockout Cattle

Myostatin (MSTN), a growth and differentiation factor, plays an important role in regulating skeletal muscle growth and development. MSTN knockout (MSTN-KO) leads to skeletal muscle hypertrophy and regulates metabolic homeostasis. Moreover, MSTN is also detected in smooth muscle. However, the effect...

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Bibliographic Details
Main Authors: Bai, C. (Author), Di, A. (Author), Gu, M. (Author), Hai, C. (Author), Li, G. (Author), Liu, X. (Author), Su, G. (Author), Wang, S. (Author), Wu, D. (Author), Yang, L. (Author)
Format: Article
Language:English
Published: MDPI 2023
Subjects:
animal
Animals
bovine
cattle
Cattle
Chromatography, Liquid
combined analysis
genetics
histidine
Histidine
knockout
liquid chromatography
metabolism
metabolome
Metabolome
metabolomics
Muscle, Skeletal
Muscle, Smooth
myostatin
Myostatin
purine derivative
Purines
skeletal muscle
smooth muscle
tandem mass spectrometry
Tandem Mass Spectrometry
transcriptome
Transcriptome
transcriptomics
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