Generation and Characterization of CYP2E1-Overexpressing HepG2 Cells to Study the Role of CYP2E1 in Hepatic Hypoxia-Reoxygenation Injury

The mechanisms of hepatic ischemia/reperfusion (I/R) injury, which occurs during liver transplantation or surgery, are poorly understood. The purpose of the current study was to generate and characterize a HepG2 cell line with a stable overexpression of CYP2E1 to investigate the role of the enzyme i...

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Main Authors: Alwadei, N. (Author), Chandrashekar, D.V (Author), Mehvar, R. (Author), Rahighi, S. (Author), Rashid, M. (Author), Sharma, A. (Author), Totonchy, J. (Author)
Format: Article
Language:English
Published: MDPI 2023
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