Whole Exome Sequencing Enhanced Imputation Identifies 85 Metabolite Associations in the Alpine CHRIS Cohort

Whole Exome Sequencing Enhanced Imputation Identifies 85 Metabolite Associations in the Alpine CHRIS Cohort

Metabolites are intermediates or end products of biochemical processes involved in both health and disease. Here, we take advantage of the well-characterized Cooperative Health Research in South Tyrol (CHRIS) study to perform an exome-wide association study (ExWAS) on absolute concentrations of 175...

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Bibliographic Details
Main Authors: Bottigliengo, D. (Author), Chan, L.S (Author), Del Greco, F.M (Author), Fuchsberger, C. (Author), Hernandes, V.V (Author), König, E. (Author), Locke, A.E (Author), Paglia, G. (Author), Pramstaller, P.P (Author), Rainer, J. (Author), Teumer, A. (Author), Yin, X. (Author)
Format: Article
Language:English
Published: MDPI 2022
Subjects:
association study
ExWAS
GWAS
imputation
metabolomics
whole-exome sequencing
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