The Meta-Substituted Isomer of TMPyP Enables More Effective Photodynamic Bacterial Inactivation than Para-TMPyP In Vitro

The Meta-Substituted Isomer of TMPyP Enables More Effective Photodynamic Bacterial Inactivation than Para-TMPyP In Vitro

Porphyrinoid-based photodynamic inactivation (PDI) provides a promising approach to treating multidrug-resistant infections. However, available agents for PDI still have optimization potential with regard to effectiveness, toxicology, chemical stability, and solubility. The currently available photo...

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Bibliographic Details
Main Authors: Eulenburg, V. (Author), Glass, S. (Author), Habermann, N. (Author), Heilmann, C. (Author), Lippmann, N. (Author), Rüffer, T. (Author), Schulz, S. (Author), Schwarz, U.T (Author), Voigt, A. (Author), Werdehausen, R. (Author), Ziganshyna, S. (Author)
Format: Article
Language:English
Published: MDPI 2022
Subjects:
antimicrobial resistance
bacterial infections
cationic porphyrins
crystallographic characterization
multi-drug resistance
photodynamic inactivation
photodynamic therapy
photosensitizer
TMPyP
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