Bioactive 2-(methyldithio)pyridine-3-carbonitrile from Persian shallot (allium stipitatum regel.) exerts broad-spectrum antimicrobial activity

Bioactive 2-(methyldithio)pyridine-3-carbonitrile from Persian shallot (allium stipitatum regel.) exerts broad-spectrum antimicrobial activity

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Antibiotic resistance is a problem that continues to challenge the healthcare sector, especially in clinically significant pathogens like methicillin-resistant Staphylococcus aureus (MRSA). Herein is described the isolation and structure elucidation of a bioactive compound from Allium stipitatum wit...

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Bibliographic Details
Main Authors: Chigurupati, S. (Author), Fauzi, F.M (Author), Ghaznavi-Rad, E. (Author), Hamat, R.A (Author), Joseph, N. (Author), Karunanidhi, A. (Author), Lung, L.T.T (Author), Nathan, J.J (Author), Neela, V. (Author), Pichika, M.R (Author), Van Belkum, A. (Author)
Format: Article
Language:English
Published: MDPI AG 2019
Subjects:
Allium stipitatum
Antibacterial
Anti-Bacterial Agents
antiinfective agent
Candida
Chemical Fractionation
chemical structure
chemistry
drug effect
fractionation
isolation and purification
methicillin resistant Staphylococcus aureus
Methicillin-resistant Staphylococcus aureus
Methicillin-Resistant Staphylococcus aureus
microbial sensitivity test
Microbial Sensitivity Tests
Minimum inhibitory concentration
Molecular Structure
nitrile
Nitriles
phytochemical
Phytochemicals
pyridine derivative
pyridine-3-carbonitrile
Pyridines
shallot
Shallots
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