Development and Evaluation of Chitosan Nanoparticles for Ocular Delivery of Tedizolid Phosphate

Development and Evaluation of Chitosan Nanoparticles for Ocular Delivery of Tedizolid Phosphate

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This study investigates the development of topically applied non-invasive chitosan-nanoparticles (CSNPs) for ocular delivery of tedizolid phosphate (TZP) for the treatment of MRSA-related ocular and orbital infections. An ionic-gelation method was used to prepare TZP-encapsulated CSNPs using tripoly...

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Bibliographic Details
Main Authors: Alkholief, M. (Author), Alshamsan, A. (Author), Alshememry, A. (Author), Iqbal, M. (Author), Kalam, M.A (Author)
Format: Article
Language:English
Published: NLM (Medline) 2022
Subjects:
animal
Animals
antibacterial
chemistry
chitosan
Chitosan
delayed release formulation
Delayed-Action Preparations
drug carrier
Drug Carriers
drug delivery system
Drug Delivery Systems
eye-irritation transcorneal-permeation
hemodialysis
Leporidae
nanoparticle
nanoparticles
Nanoparticles
organophosphate
Organophosphates
oxazole derivative
Oxazoles
particle size
Particle Size
pharmacology
Rabbits
Renal Dialysis
tedizolid
tedizolid-phosphate
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