Structure-Based Virtual Screening towards the Discovery of Novel ULK1 Inhibitors with Anti-HCC Activities

There is an urgent need to develop new effective therapies for HCC. Our previous study identified ULK1 as the potential target for HCC therapy and screened the compound XST-14 as a specific inhibitor of ULK1 to suppress HCC progression. However, the poor manufacturability of XST-14 impeded the proce...

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Bibliographic Details
Main Authors: Gao, Y. (Author), Jiang, J. (Author), Li, K. (Author), Xue, S. (Author), Zhang, T. (Author), Zhou, Z. (Author)
Format: Article
Language:English
Published: MDPI 2022
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Online Access:View Fulltext in Publisher