1,2,3-Triazolyl-tetrahydropyrimidine Conjugates as Potential Sterol Carrier Protein-2 Inhibitors: Larvicidal Activity against the Malaria Vector Anopheles arabiensis and In Silico Molecular Docking Study

1,2,3-Triazolyl-tetrahydropyrimidine Conjugates as Potential Sterol Carrier Protein-2 Inhibitors: Larvicidal Activity against the Malaria Vector Anopheles arabiensis and In Silico Molecular Docking Study

Alteration of insect growth regulators by the action of inhibitors is becoming an attractive strategy to combat disease-transmitting insects. In the present study, we investigated the larvicidal effect of 1,2,3-triazolyl-pyrimidinone derivatives against the larvae of the mosquito Anopheles arabiensi...

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Main Authors: Al-Shar’i, N.A (Author), Asdaq, S.M.B (Author), Attimarad, M. (Author), Chandrashekharappa, S. (Author), Chopra, D. (Author), Deb, P.K (Author), Gleiser, R.M (Author), Haroun, M. (Author), Kandeel, M. (Author), Mahomoodally, F.M (Author), Mohanlall, V. (Author), Morsy, M.A (Author), Nair, A.B (Author), Shinu, P. (Author), Sreeharsha, N. (Author), Tratrat, C. (Author), Venugopala, K.N (Author)
Format: Article
Language:English
Published: MDPI 2022
Subjects:
Anopheles arabiensis
Biginelli reaction
Click chemistry
In silico docking
Molecular hybridization
Mosquito larvicidal activity
Pyrimidine
Sterol carrier protein-2
Triazole
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