Influence of the encapsulation efficiency and size of liposome on the oral bioavailability of griseofulvin-loaded liposomes

Influence of the encapsulation efficiency and size of liposome on the oral bioavailability of griseofulvin-loaded liposomes

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The objective of the present study was to investigate the influence of the encapsulation efficiency and size of liposome on the oral bioavailability of griseofulvin-loaded liposomes. Griseofulvin-loaded liposomes with desired characteristics were prepared from pro-liposome using various techniques....

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Bibliographic Details
Main Authors: Lee, K.S (Author), Ming, L.C (Author), Ong, S.G.M (Author), Yuen, K.H (Author)
Format: Article
Language:English
Published: MDPI AG 2016
Subjects:
animal experiment
area under the curve
Article
controlled study
drug absorption
drug bioavailability
drug blood level
drug determination
drug dosage form comparison
drug formulation
drug structure
encapsulation
griseofulvin
Griseofulvin
in vivo study
liposomal delivery
liposome
Liposomes
male
maximum plasma concentration
nonhuman
Oral administration
particle size
Poorly bioavailable drug
rat
time to maximum plasma concentration
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