Differential Dynamics of Humoral and Cell-Mediated Immunity with Three Doses of BNT162b2 SARS-CoV-2 Vaccine in Healthcare Workers in Japan: A Prospective Cohort Study

Differential Dynamics of Humoral and Cell-Mediated Immunity with Three Doses of BNT162b2 SARS-CoV-2 Vaccine in Healthcare Workers in Japan: A Prospective Cohort Study

Vaccines against SARS-CoV-2 with good efficacy are now available worldwide. However, gained immunity diminishes over time. Here, we investigate the course of both humoral and cell-mediated immunity in response to three doses of the Pfizer mRNA BNT162b2 SARS-CoV-2 vaccine in healthcare workers in Jap...

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Bibliographic Details
Main Authors: Furuhashi, K. (Author), Iwaizumi, M. (Author), Maekawa, M. (Author), Nagura, O. (Author), Niizeki, N. (Author), Ogitani, K. (Author), Suzuki, A. (Author), Takebayashi, S. (Author), Toguchi, A. (Author), Yamashita, K. (Author)
Format: Article
Language:English
Published: MDPI 2022
Subjects:
antibody avidity
anti-RBD antibody
BNT162b2 vaccine
cell-mediated immunity
ELISpot-
harmonize
humoral immunity
SARS-CoV-2
T-SPOT
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