Atheroprotective effects of pure tocotrienol supplementation in the treatment of rabbits with experimentally induced early and established atherosclerosis

Atheroprotective effects of pure tocotrienol supplementation in the treatment of rabbits with experimentally induced early and established atherosclerosis

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Background: Atherosclerosis is the main cause of coronary artery disease-related deaths worldwide. The atheroprotective properties of pure tocotrienols (T3) in the absence of alpha-tocopherol (α-TCP) in Vitamin E has not been extensively examined. Aim: To determine the atheroprotective properties of...

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Bibliographic Details
Main Authors: Abdul Rahman, T. (Author), Hassim, N.F (Author), Kornain, N.K (Author), Muid, S. (Author), Nawawi, H. (Author), Zulkafli, N. (Author)
Format: Article
Language:English
Published: Taylor and Francis Ltd. 2016
Subjects:
alpha tocotrienol
animal experiment
animal model
animal tissue
aorta
aortic atherosclerosis
aortic endothelial cell
Article
Atherosclerosis
atherosclerotic plaque
cell activation
controlled study
Delta tocotrienol
dose response
drug dose comparison
drug effect
drug potency
endothelial leukocyte adhesion molecule 1
experimental arteriosclerosis
experimental atherosclerosis
Gamma tocotrienol
gelatinase B
heart protection
Hypercholesteroleamic rabbits
inflammation
interleukin 6
isomer
lipid
lipid analysis
lipid blood level
macrophage elastase
New Zealand White (rabbit)
nonhuman
placebo
protein expression
supplementation
Tissue biomarker
vascular cell adhesion molecule 1
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