Starvation mediates pancreatic cancer cell sensitivity to ferroptosis via ERK1/2, JNK and changes in the cell mesenchymal state

Pancreatic cancer is a highly metastatic and therapy‑resistant disease. In the present study, the prospects of a novel approach to kill pancreatic cancer cells were examined: Starvation combined with ferroptosis induction. Established pancreatic cancer cell lines (Miapaca2, Panc&#x201...

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Bibliographic Details
Main Authors: Cicenas, J. (Author), Zalyte, E. (Author)
Format: Article
Language:English
Published: NLM (Medline) 2022
Subjects:
JNK
Online Access:View Fulltext in Publisher