Total flavonoids of Rhizoma Drynariae enhances CD31hiEmcnhi vessel formation and subsequent bone regeneration in rat models of distraction osteogenesis by activating PDGF‑BB/VEGF/RUNX2/OSX signaling axis

Total flavonoids of Rhizoma Drynariae enhances CD31hiEmcnhi vessel formation and subsequent bone regeneration in rat models of distraction osteogenesis by activating PDGF‑BB/VEGF/RUNX2/OSX signaling axis

Total flavonoids of Rhizoma Drynariae (TFRD), extracted from the kidney‑tonifying Traditional Chinese medicine Rhizoma Drynariae, can be effective in treating osteoporosis, bone fractures and defects. However, the pharmacological effects of TFRD on the specific vessel subtype CD31hiEmcnhi during dis...

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Bibliographic Details
Main Authors: Chen, G. (Author), Chen, H. (Author), Chen, Z. (Author), Dong, W. (Author), Guo, Y. (Author), Huang, M. (Author), Jiang, Z. (Author), Li, Z. (Author), Lin, H. (Author), Shen, Z. (Author), Zhang, Y. (Author)
Format: Article
Language:English
Published: NLM (Medline) 2022
Subjects:
bone regeneration
CD31hiEmcnhi vessels
distraction osteogenesis
platelet‑derived growth factor‑BB
total flavonoids of Rhizoma Drynariae
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