Lactate receptor HCAR1 regulates cell growth, metastasis and maintenance of cancerspecific energy metabolism in breast cancer cells
under aerobic conditions, the preferential use of anaerobic glycolysis by tumour cells leads to a high level of lactate accumulation in tumour microenvironment. lactate acts not only as a cellular energy source but also as a signal ling molecule that regulates cancer cell growth, metastasis and meta...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Spandidos Publications
2022
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| Subjects: | |
| Online Access: | View Fulltext in Publisher |