Nordamnacanthal potentiates the cytotoxic effects of tamoxifen in human breast cancer cells

Nordamnacanthal potentiates the cytotoxic effects of tamoxifen in human breast cancer cells

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Tamoxifen (TAM) is the mainline drug treatment for breast cancer, despite its side effects and the development of resistance. As an alternative approach, in the present study a novel combination therapy was established through combining TAM with nordamnacanthal (NDAM) in order to investigate the add...

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Bibliographic Details
Main Authors: Alitheen, N.B (Author), Ho, C.L (Author), Ho, W.Y (Author), Ismail, N.H (Author), Osman, C.P (Author), Rahman, N.M.A.N.A (Author), Subramani, T. (Author), Yeap, S.K (Author)
Format: Article
Language:English
Published: Spandidos Publications 2015
Subjects:
anthraquinone derivative
apoptosis
Apoptosis
Article
breast cancer
Breast cancer
cell cycle assay
cell proliferation
cell viability
Combination treatment
controlled study
cytotoxicity
flow cytometry
human
human cell
lipid peroxidation
lipocortin 5
MCF-7
mitochondrial membrane potential
MTT assay
nordamnacanthal
Nordamnacanthal
reactive oxygen metabolite
tamoxifen
Tamoxifen
unclassified drug
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