Optimal control in pharmacokinetic drug administration
We consider a two-box model for the administration of a therapeutic substance and discuss two scenarios: First, the substance should have an optimal therapeutic concentration in the central compartment (typically blood) and be degraded in an organ, the peripheral compartment (e.g., the liver). In th...
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| Format: | Article |
| Language: | English |
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American Institute of Mathematical Sciences
2022
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| Online Access: | View Fulltext in Publisher |