Performance of international aids vaccine initiative african clinical research laboratories in standardised elispot and peripheral blood mononuclear cell processing in support of HIV vaccine clinical trials

Performance of international aids vaccine initiative african clinical research laboratories in standardised elispot and peripheral blood mononuclear cell processing in support of HIV vaccine clinical trials

Background: Standardisation of procedures for performing cellular functional assays across laboratories participating in multicentre clinical trials is key for generating comparable and reliable data. Objective: This article describes the performance of accredited laboratories in Africa and Europe o...

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Bibliographic Details
Main Authors: Anzala, O. (Author), Bizimana, J. (Author), Chetty, P. (Author), Cox, J.H (Author), Dally, L. (Author), Farah, B. (Author), Gilmour, J. (Author), Hayes, P. (Author), Hills, N. (Author), Indangasi, J. (Author), Jangano, M. (Author), Langat, R.K (Author), Muyanja, E. (Author), Ngetsa, C. (Author), Ogola, S. (Author), Omosa-Manyonyi, G. (Author), Silwamba, M. (Author), Tekirya, E. (Author)
Format: Article
Language:English
Published: AOSIS OpenJournals Publishing AOSIS (Pty) Ltd 2021
Subjects:
Article
blood donor
cell isolation
cell processing
cell viability
clinical laboratory
Clinical trials
controlled study
Cytomegalovirus
ELISpot
enzyme linked immunospot assay
Epstein Barr virus
Good clinical laboratory practice
human
human cell
Human immunodeficiency virus infection
Human immunodeficiency virus vaccine
Influenza virus
Kenya
PBMC processing
peripheral blood mononuclear cell
Peripheral blood mononuclear cells
procedures concerning cells
Proficiency testing
Rwanda
South Africa
Uganda
Zambia
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