Quantification of abemaciclib and metabolites: Evolution of bioanalytical methods supporting a novel oncolytic agent

Aim: Bioanalytical methods undergo many revisions and modifications throughout drug development to meet the objectives of the study and development program. Results: Validated LC-MS/MS methodology used to quantify abemaciclib and four metabolites in human plasma is described. The method, initially v...

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Bibliographic Details
Main Authors: Lee, L.B (Author), Wickremsinhe, E.R (Author)
Format: Article
Language:English
Published: Future Medicine Ltd. 2021
Subjects:
Online Access:View Fulltext in Publisher