Validation of high-throughput, semiquantitative solid-phase SARS coronavirus-2 serology assays in serum and dried blood spot matrices

Validation of high-throughput, semiquantitative solid-phase SARS coronavirus-2 serology assays in serum and dried blood spot matrices

Aim: Serological assays for the detection of anti-SARS coronavirus-2 (SARS-CoV-2) antibodies are essential to the response to the global pandemic. A ligand binding-based serological assay was validated for the semiquantitative detection of IgG, IgM, IgA and neutralizing antibodies (nAb) against SARS...

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Bibliographic Details
Main Authors: Bennett, A.C (Author), Bouic, P.J (Author), Devine, J. (Author), Kimberg, M. (Author), Lapierre, F. (Author), Maritz, L. (Author), Soares, A. (Author), Woudberg, N.J (Author)
Format: Article
Language:English
Published: Future Medicine Ltd. 2021
Subjects:
antibody detection
Article
bioassay
Biological Assay
blood
controlled study
coronavirus disease 2019
COVID-19
diagnostic test accuracy study
dried blood spot
dried blood spot testing
Dried Blood Spot Testing
ELISA
enzyme linked immunosorbent assay
Healthy Volunteers
high throughput analysis
high throughput screening
High-Throughput Screening Assays
human
human cell
Humans
immunoglobulin A
immunoglobulin G
immunoglobulin M
in vitro study
neutralizing antibodies
neutralizing antibody
normal human
pathogenicity
procedures
quantitative analysis
receptor binding assay
reproducibility
Reproducibility of Results
SARS-CoV-2
sensitivity and specificity
serology
serum
Severe acute respiratory syndrome coronavirus 2
solid
validation process
virus neutralization
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