Assessing the impact of nonspecific binding on oligonucleotide bioanalysis

Aim: Accurate and reliable quantification of oligonucleotides can be difficult, which has led to an increased focus on bioanalytical methods for more robust analyses. Recent advances toward mitigating sample losses on liquid chromatography (LC) systems have produced recovery advantages for oligonucl...

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Bibliographic Details
Main Authors: Donegan, M. (Author), Gilar, M. (Author), Koshel, B. (Author), Lauber, M.A (Author), Li, Z. (Author), Maclean, J. (Author), Nguyen, J.M (Author)
Format: Article
Language:English
Published: Future Medicine Ltd. 2021
Subjects:
pH
Online Access:View Fulltext in Publisher