Synthesis of some new propanamide derivatives bearing 4-piperidinyl-1,3,4-oxadiazole, and their evaluation as promising anticancer agents
Purpose: To sequentially synthesize piperidine-4-carboxylic acid ethyl ester-appended 1,3,4-oxadiazole hybrids and to evaluate them as anticancer agents. Methods: Ethyl 1-[(4-methylphenyl)sulfonyl]-4-piperidinecarboxylate (1) was synthesized from 4-methylbenzenesulfonylchloride (a) and ethyl 4-piper...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
University of Benin
2018
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Subjects: | |
Online Access: | View Fulltext in Publisher View in Scopus |