Expression of hMLH1 and hMSH2 proteins in ameloblastomas and tooth germs

Expression of hMLH1 and hMSH2 proteins in ameloblastomas and tooth germs

Background: Mismatch repair proteins (MMRPs) are a group of nuclear enzymes that participate in the repair of base mismatches that occur during DNA replication in all proliferating cells. The most studied MMRPs are hMSH2 and hMLH1, which are known to be highly expressed in normal tissues. A loss of...

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Bibliographic Details
Main Authors: Bologna-Molina, R. (Author), Gónzalez-Gónzalez, R. (Author), Hernandez, M. (Author), Mikami, T. (Author), Molina-Frechero, N. (Author), Pereira-Prado, V. (Author), Sánchez-Romero, C. (Author), Soria, S. (Author), Tapia-Repetto, G. (Author)
Format: Article
Language:English
Published: Medicina Oral S.L. 2018
Subjects:
ameloblastoma
Ameloblastoma
Ameloblastomas
Article
biosynthesis
carcinogenesis
cell proliferation
cell proliferation assay
controlled study
deacetylation
DNA methylation assay
DNA mismatch repair protein MSH2
DNA repair
DNA replication
gene expression
gene mutation
genetic analysis
histone acetylation
HMLH1
HMSH2
human
human cell
human tissue
Humans
immunohistochemistry
Immunohistochemistry
Jaw Neoplasms
jaw tumor
Ki 67 antigen
Ki-67
Ki-67 Antigen
major clinical study
metabolism
mismatch repair protein
MLH1 protein, human
MSH2 protein, human
MutL protein homolog 1
MutL Protein Homolog 1
MutS Homolog 2 Protein
next generation sequencing
observational study
odontogenic tumor
protein expression
tooth germ
Tooth Germ
Tooth germs
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