Diethylhexyl phthalate induced oxidative stress and caused metabolic imbalance in bone marrow mesenchymal stem cells

Diethylhexyl phthalate induced oxidative stress and caused metabolic imbalance in bone marrow mesenchymal stem cells

Introduction: Diethylhexyl phthalate (DEHP) is leaching form polyvinyl chloride to cause animal toxicity. In our previous study, DEHP caused osteoblasts mortality in vitro, since rat bone marrow mesenchymal stem cells (MSCs) is the cellular back up for osteoblasts; therefore its effect on MSCs was i...

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Bibliographic Details
Main Authors: Abnosi, M.H (Author), Babolghani, Z.A (Author)
Format: Article
Language:English
Published: Iranian Society of Physiology and Pharmacology 2022
Subjects:
acridine orange
alanine aminotransferase
animal cell
antioxidant assay
Article
aspartate aminotransferase
biochemical analysis
bone marrow mesenchymal stem cell
calcium
catalase
cell density
cell isolation
cell proliferation
cell structure
Cell survival
cell ultrastructure
cell viability
colony forming unit
colorimetry
controlled study
Diethylhexyl phthalate
enzyme linked immunosorbent assay
Enzymes assay
flow cytometry
fluorescence microscopy
hemocytometry
lactate dehydrogenase
lipid peroxidation
male
malonaldehyde
mean cytoplasmic area
Mesenchymal stem cell
metabolic balance
MTT assay
nonhuman
nuclei diameter
osteoblast
oxidative stress
Oxidative stress
phthalic acid bis(2 ethylhexyl) ester
potassium
rat
sodium
spectrophotometry
superoxide dismutase
tetrazolium
trypan blue assay
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