Formulation and characterization of pH induced in situ gels containing sulfacetamide sodium for ocular drug delivery: A combination of Carbopol®/HPMC polymer

Formulation and characterization of pH induced in situ gels containing sulfacetamide sodium for ocular drug delivery: A combination of Carbopol®/HPMC polymer

Introduction: Topical delivery of eye drops which currently accounts to 90% of available ocular dosage forms are ideal for the treatment of eye diseases but having limitations of poor therapeutic response and low bioavailability. Objectives: The objectives of present research was to develop and char...

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Bibliographic Details
Main Authors: Dua, K. (Author), Kok, Y.Y (Author), Ming, N.J (Author), Sheshala, R. (Author), Singh, T.R.R (Author)
Format: Article
Language:English
Published: Association of Pharmaceutical Teachers of India 2019
Subjects:
antimicrobial activity
Antimicrobial efficacy
Article
carbomer
Carbopol®/HPMC
chemical composition
controlled study
drug analysis
drug delivery system
drug formulation
drug release
drug solubility
drug stability
drug sterility
encapsulation
Escherichia coli
flow kinetics
flow measurement
gelling agent
human
hydroxypropylmethylcellulose
In situ gel
in vitro study
In-vitro release
kinetics
Klebsiella pneumoniae
Ocular
pH
polymer
Staphylococcus aureus
sulfacetamide
Sulfacetamide sodium
sustained drug release
sustained release preparation
ultraviolet visible spectrophotometry
viscosity
zone of inhibition
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