Pharmacophore Modeling, Docking, and Molecular Dynamics Simulation of Flavonoids as Inhibitors of Urokinase-type Plasminogen Activator
The urokinase-type plasminogen activator (uPA) system plays a significant role in the invasion and metastasis of cancer cells. The present study was conducted to investigate natural product compounds as inhibitors and hit molecules of uPA using in-silico analysis. A pharmacophore model was built to...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Institute for Research and Community Services, Institut Teknologi Bandung
2021
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| Subjects: | |
| Online Access: | View Fulltext in Publisher |