Enhanced C/EBPβ function promotes hypertrophic versus hyperplastic fat tissue growth and prevents steatosis in response to high-fat diet feeding

Chronic obesity is correlated with severe metabolic and cardiovascular diseases as well as with an increased risk for developing cancers. Obesity is usually characterized by fat accumulation in enlarged-hypertrophic – adipocytes that are a source of inflammatory mediators, which promote the developm...

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Bibliographic Details
Main Authors: Calkhoven, C.F (Author), Eichwald, S. (Author), Kortman, G. (Author), Koster, M.H (Author), Müller, C. (Author), Zidek, L.M (Author)
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022
Online Access:View Fulltext in Publisher