Masking residues using context-specific evolutionary conservation significantly improves short linear motif discovery
Motivation: Short linear motifs (SLiMs) are important mediators of protein-protein interactions. Their short and degenerate nature presents a challenge for computational discovery. We sought to improve SLiM discovery by incorporating evolutionary information, since SLiMs are more conserved than su...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
2009.
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| Subjects: | |
| Online Access: | Get fulltext |