Disruption of neuronal function by soluble hyperphosphorylated tau in a Drosophila model of tauopathy
Axonal microtubules are essential for transport of materials to the synapse. Compromised microtubules and synaptic loss have been demonstrated in AD (Alzheimer's disease), which is believed to contribute to cognitive dysfunction before neuronal death in the early stages of the disease. The me...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
2010-04.
|
Subjects: | |
Online Access: | Get fulltext |