Microfluidic-based measurements of cytochrome P450 enzyme activity of primary mammalian hepatocytes
A microfluidic-based system was developed for the in situ monitoring of the 7-ethoxyresorufin O-dealkylation (EROD) activity of primary rat hepatocytes by measuring the fluorescent intensity of both cells and their surrounding media. The microfluidic chip was designed to allow the cell suspension an...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
2010-05.
|
Subjects: | |
Online Access: | Get fulltext |