Presence of nonhemolytic pneumolysin in serotypes of streptococcus pneumoniae associated with disease outbreaks

Pneumolysin is an important virulence factor of the human pathogen Streptococcus pneumoniae. Sequence analysis of the ply gene from 121 clinical isolates of S. pneumoniae uncovered a number of alleles. Twenty?two strains were chosen for further analysis, and 14 protein alleles were discovered. Five...

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Main Authors: Jefferies, Johanna M.C (Author), Johnston, Calum H.G (Author), Kirkham, Lea-Ann S. (Author), Cowan, Graeham J.M (Author), Ross, Kirsty S. (Author), Smith, Andrew (Author), Clarke, Stuart C. (Author), Brueggeman, Angela B. (Author), George, Robert C. (Author), Pichon, Bruno (Author), Pluschke, Gerd (Author), Pfluger, Valentin (Author), Mitchell, Tim J. (Author)
Format: Article
Language:English
Published: 2007-09-15.
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