Genetic loci influencing kidney function and chronic kidney disease

Genetic loci influencing kidney function and chronic kidney disease

Using genome-wide association, we identify common variants at 2p12-p13, 6q26, 17q23 and 19q13 associated with serum creatinine, a marker of kidney function (P = 10?10 to 10?15). Of these, rs10206899 (near NAT8, 2p12-p13) and rs4805834 (near SLC7A9, 19q13) were also associated with chronic kidney dis...

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Main Authors: Chambers, John C (Author), Zhang, Weihua (Author), Lord, Graham M (Author), van der Harst, Pim (Author), Lawlor, Debbie A (Author), Sehmi, Joban S (Author), Gale, Daniel P (Author), Wass, Mark N (Author), Ahmadi, Kourosh R (Author), Bakker, Stephan J L (Author), Beckmann, Jacqui (Author), Bilo, Henk J G (Author), Bochud, Murielle (Author), Brown, Morris J (Author), Caulfield, Mark J (Author), Connell, John M C (Author), Cook, H Terence (Author), Cotlarciuc, Ioana (Author), Smith, George Davey (Author), de Silva, Ranil (Author), Deng, Guohong (Author), Devuyst, Olivier (Author), Roderick, Paul (Author), Dikkeschei, Lambert D (Author), Dimkovic, Nada (Author), Dockrell, Mark (Author)
Format: Article
Language:English
Published: 2010-05.
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